The focus of our research is the modulation of secondary injury cascades and the
application of stem cells in the treatment of traumatic injuries, particularly injury
to tissues that have poor intrinsic healing. Specifically, we are testing strategies
that combine stem bone marrow derived progenitor cells and novel matrices to repair
injuries to cartilage and peripheral nerves. We are developing novel stem cell lines
that have enhance proliferative capacity and are exploring ways to use them to enhance
tissue repair either as direct contributors to tissue formation or as a source of
growth factors to stimulate local endogenous repair cells.
Selected Publications
Lee E, Kim HT. Early fatigue failures of cemented, forged
cobalt-chromium femoral stems at the neck-shoulder junction. Journal of Arthroplasty. 2001 16(2):236-8.
Costouros JG, Dang AC, Kim HT. Inhibition of chondrocyte apoptosis in vivo following
osteochondral injury. Osteoarthritis and Cartilage. 2003 11(10):756-759.
Piper SL, Kim HT. Ropivicaine is less cytotoxic than
bupivicaine to human articular chondrocytes. Journal of Bone and Joint Surgery-A. In press.
Information last updated September 2007
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